I've somehow managed to get this overlay stuck in the top right corner of my screen, and I can't figure out how to get rid of it. I think it might be related to my Radeon graphics, but none of the hotkeys I'm trying seem to remove it permanently. I've added a photo in the comments for reference.
2 Answers
You can also try this: right-click on your desktop, select 'AMD Software: Adrenalin Edition', go to 'Settings' (the gear icon), and then find 'In-Game Overlay' to toggle it off. If that doesn’t help, check the Performance section and turn off 'Show Metrics Overlay' as well. This usually does the trick!
Try pressing Alt + R; that usually works to toggle overlays off. However, if that doesn't do it, there's a chance it’s part of the AMD software. You might also want to check your settings there.

Nope, that didn't work for me either! It just keeps popping back.