How Can I Secure My USB Drive with Python?

Adjusting permissions will only protect you on devices you control. If someone plugs your USB into a different computer, those settings won't matter. So while you can prevent accidental changes, be aware that it won't stop someone from accessing your files if they get hold of the drive.

You could definitely use the `os` library! Check out the `os.chmod` function to change file permissions. If you're using Pathlib, Path objects have a `chmod` method too. Just keep in mind, the effectiveness of this varies between operating systems. For Windows, `chmod` mainly sets the 'read-only' flag. If you're looking for encryption, consider using the `cryptography.fernet` package. Just remember to keep your key safe!

Just a heads up, relying solely on USB drives for important files isn't the best idea. They tend to have a shorter lifespan compared to other storage options.