Is upgrading from 32GB to 48GB of RAM worthwhile?

It really depends on what you do with the computer. For gaming, 32GB is generally plenty, and adding more usually won’t improve performance. A mismatched setup may also run in a less optimal memory mode. For demanding work such as video editing, 3D rendering, large spreadsheets, or running virtual machines, extra capacity can be worthwhile even if performance isn’t perfectly optimized.

Those capacities are common because memory modules are built from chips organized in binary sizes, so capacities tend to double: 8, 16, 32, and 64GB. There’s nothing inherently wrong with 48GB, but it’s less straightforward than using a balanced matched configuration. For gaming, I’d keep the existing 32GB unless you’re actually running out of memory.

All installed memory will normally run at the speed and timings supported by the slowest stick or kit. For example, adding slower RAM to a faster kit can make the whole system operate at the slower setting. Mixing kits can also cause instability, even when the specifications appear identical, so check your motherboard’s memory support list and be prepared to lower the speed if necessary.

If you’re adding two 8GB sticks to your existing two 16GB sticks, many systems can use the matching portions in dual-channel mode, sometimes called flex mode. However, the exact behavior depends on the motherboard and CPU, and four sticks can be more difficult to run at high memory speeds. It’s usually best to use one matched 2-stick kit, such as 2×32GB, if you truly need 64GB.