I recently replaced my Ryzen 5 3600 with a Ryzen 9 5950X in an ASRock B550M Pro4 system. The rest of the build includes an RTX 5060 Ti 16GB, 32GB of DDR4-3200 using four 8GB sticks, and a Noctua NH-U15 cooler. After the CPU upgrade, I started getting repeated Event 41 errors and instability. I originally used a Seasonic GM650 Gold power supply, then replaced it with a Gigabyte UD750GM PG5 V2 Ice 750W ATX 3.1 unit because I suspected the PSU. I have tried BIOS versions 4.00 and 3.90, forcing PCIe Gen 3, testing with one and two RAM sticks, running the memory at its default 2400MHz, using Eco Mode and manual settings, limiting GPU power to 80%, and changing CPU power-state and PBO settings. None of these made a difference. The system is stable when I reinstall the Ryzen 5 3600, so I'm running out of ideas about whether the 5950X, motherboard, or another component is responsible.
2 Answers
Double-check that both motherboard power connectors are fully inserted, including the CPU power connector, and also verify the PSU-side connections if the cables are modular. The ASRock board is the motherboard here, while Gigabyte is the PSU manufacturer. Even when a connector looks connected, it may not be fully latched, so reseat both ends carefully.
Put the Ryzen 5 3600 back in and test the system under the same conditions. If the older CPU runs normally while the 5950X consistently triggers the errors, that points more toward the new CPU or a motherboard/firmware compatibility issue than the graphics card or power supply.
I tried reinstalling the 3600, and the system is stable again with that processor.

The board is an ASRock B550M Pro4 and the power supply is the Gigabyte unit. I checked the cables and confirmed that they are locked in.