Windows Stops Responding to Clicks Even Though the Cursor Still Moves

While browsing in Chrome, my computer suddenly started navigating back to the previous page or tab as if the Back button were being pressed repeatedly. Restarting Chrome did not help, and shortly afterward I could no longer click anything at all—not Chrome, the desktop, or even the taskbar. The cursor moves normally and there is no noticeable lag, but clicks have no effect. I have already restarted the computer and also forced it to power off, but the issue keeps returning within about a minute. I recently started customizing Windows with Windhawk, so I'm wondering whether that could be related. What should I check to figure out whether this is a software, keyboard, or mouse problem?