I'm running Windows 11 Pro on a Ryzen 5 7600X with a Gigabyte B650M Gaming X AX motherboard, 32 GB of RAM currently operating in single-channel mode, and a Radeon RX 9070. My wired mouse randomly stops responding for one or two seconds, sometimes after a few minutes and sometimes only after several hours. It also happens during light web browsing, not just under heavy load.
A wireless mouse behaves the same way, and I've tried different USB ports, including USB 2.0 and USB 3.x. USB monitoring tools show the device disconnecting, although Event Viewer does not consistently log a driver error. Windows, BIOS, AMD chipset drivers, and graphics drivers are up to date. I've also disabled USB selective suspend, changed power plans, disabled C-states, checked temperatures, and looked for 5V power drops without finding anything obvious.
The RAM has been running single-channel because two motherboard socket pins appear bent and could not be corrected. The system worked normally for about two years, though. The power supply is an older Corsair VS650. What else should I test to determine whether this is a USB controller, memory configuration, TPM, or power-supply problem?
3 Answers
Another possibility is a TPM-related stutter rather than a physical USB disconnect. Check whether the pauses correspond to TPM or firmware events in Windows logs, and confirm that your BIOS and AMD firmware components are current. I would avoid permanently disabling TPM until you understand the consequences, especially if Windows encryption or other security features use it; treat that only as a controlled troubleshooting test.
The single-channel memory and the damaged motherboard socket pins are worth taking seriously. Ryzen systems can be sensitive to memory configuration, and a marginal board or memory connection could cause brief system-wide stalls that look like USB failures. If both memory sticks are still usable, test them individually and verify they are installed in the recommended slots. Run a proper memory test as well. If the socket damage affects the memory channels, the long-term fix may require motherboard repair or replacement.
Since the issue affects both wired and wireless mice, the mouse and its cable are probably not the cause. This points more toward the motherboard’s USB controller, a system-wide pause, or a brief power issue. In Device Manager, open every USB Root Hub and Generic USB Hub, then check the Power Management tab and disable “Allow the computer to turn off this device to save power.” Also make sure the chipset drivers came directly from AMD rather than only through Windows Update. If possible, test with a known-good power supply, since an aging 650W unit could cause brief brownouts that appear first as USB dropouts.
I installed the chipset drivers directly from the manufacturer, and the problem seems less frequent now, but the disconnects still happen occasionally.
I haven’t tested the TPM angle yet. I’ll check the relevant BIOS and Windows settings before changing anything permanently.