Which Linux distribution is best for work and gaming on my AMD PC?

Debian KDE is another option, but the testing branch probably isn’t the easiest choice for a first Linux installation. A stable release or Fedora-based system will usually involve less troubleshooting while you’re getting used to Linux.

The desktop environment may matter more than the distribution at first. KDE and GNOME are the two most common choices, so it’s worth watching a few videos or testing them in a virtual machine before deciding. KDE will probably feel more comfortable coming from Windows, especially with multiple monitors and a desire to customize things.

You don’t normally install DirectX separately on Linux. Steam’s Proton translates many DirectX calls into Vulkan and creates the Windows-like environment needed by the game. Proton also supplies or installs common Visual C++ and other Windows runtime components when required. Steam makes this fairly seamless, though compatibility still varies by game, especially for titles with strict anti-cheat systems.

Bazzite and CachyOS can both be enjoyable, but Fedora is a simpler starting point if you want a conventional desktop and straightforward maintenance. Bazzite is especially gaming-focused, while CachyOS emphasizes performance and newer packages. I’d start with Fedora KDE, test your work applications and favorite games from a live USB or spare drive, and keep regular backups.

Fedora KDE sounds like a strong fit. KDE is fairly familiar if you’re coming from Windows, while still being highly customizable, and Fedora’s current AMD graphics support should work well with your hardware. Zoom works, and Teams can be used through a web browser. Dual-monitor setups generally work, although some applications may occasionally have scaling issues when moving between monitors. For gaming, Steam handles Proton automatically, and Heroic is useful for GOG and Epic games.