Can an HP Z620 power an RX 580 with 6-pin and 8-pin connectors?

The Z620 does not use a standard ATX power supply, so replacing it with a normal modern PSU is not straightforward. Its factory PSU and motherboard wiring are proprietary, and the available GPU power connections are generally intended for 6-pin plugs. Do not assume that a random 8-pin adapter has the correct pinout—an incorrectly wired adapter could damage the graphics card, power supply, or system. Verify the exact connector wiring before using one.

The Z620’s total wattage rating is not the only concern. Its power supply distributes power across several smaller rails and was designed around specific workstation components, rather than one large modern 12V rail. Even if the overall wattage looks sufficient, adding a high-draw GPU through improvised adapters may overload a connector or individual rail. A lower-power graphics card with connectors that match the workstation, or a properly documented Z620-compatible GPU power solution, would be safer.

Check the exact RX 580 model first. Many RX 580 cards only require one 8-pin connector, while higher-clocked versions may require a 6-pin plus an 8-pin or even two 8-pins. The connector requirement varies by manufacturer, so the card’s label or specification sheet matters more than the RX 580 name alone.