How Can I Get Single-Click Interaction with Unfocused Windows on Linux?

I've been using Linux on and off for quite some time, and while I really appreciate its performance—especially in comparison to Windows 11, particularly for gaming—I'm facing a frustrating issue that prevents me from fully committing to it as my main operating system. My main problem lies in how I interact with unfocused windows. Let me give you an example: I often play RuneScape and keep the wiki open on my second monitor. I want to be able to click a checkbox on the wiki while I'm still focused on the game. The behavior I expect is to simply drag my cursor over to the second monitor, click the checkbox (which would focus that window and register the click simultaneously), and then go back to the game with a single click to continue playing. However, what actually happens is that I have to click once to focus the window, then click again to check the box. Then, when I return to the game, I need to click twice to resume. This makes it annoying to navigate between the two without interruption. How can I achieve this smoother interaction?