I still need to buy the drive for my operating system, but NVMe SSD prices are much higher where I live. I understand that NVMe drives can be several times faster than regular SATA SSDs, yet similarly sized models from the same brands often have comparable endurance ratings. For a system used for gaming, general use, development, and design work, will I notice a meaningful difference, and is NVMe worth paying substantially more for?
3 Answers
NVMe drives use PCIe, while SATA SSDs are limited to roughly 550–600 MB/s. Depending on the PCIe generation, an NVMe drive can reach several thousand MB/s. Those headline numbers do not translate directly into faster boot times, though. Game loading may improve somewhat, and newer games that make heavy use of storage streaming can benefit, but it is not usually a night-and-day upgrade.
Endurance is not determined only by whether the drive is SATA or NVMe. It depends on the flash type, controller, capacity, and warranty. Both types can handle normal heavy desktop use for many years. NVMe drives can run hotter under sustained workloads, so good airflow or a motherboard heatsink may help. If you need the drive now and NVMe costs dramatically more, buy a quality SATA SSD rather than overspending just for benchmark numbers.
The practical difference depends heavily on what you do. NVMe is much faster for large file transfers, installing or compiling large projects, and workloads that constantly read and write data. For booting the operating system, launching most applications, and everyday gaming, the difference from a good SATA SSD is usually fairly small. If the price gap is large, SATA can still be a perfectly good choice.

For gaming, general use, development, and design, I would prioritize capacity, reliability, and a decent controller over the absolute highest sequential speed. A moderately priced NVMe drive is a nice default if your motherboard supports it, but a much cheaper SATA SSD is still reasonable.