Hey everyone! I'm working on building an advanced workstation for my machine learning projects, and I could really use some advice on cooling. Here's what I'm planning to use:
- AMD Threadripper Pro 9995WX (96 cores)
- ASUS Pro WS WRX90E-SAGE SE motherboard
- 512GB DDR5 ECC RAM (8x64GB)
- 2x RTX 5090 Founders Edition GPUs
- Seasonic Prime TX-1600 power supply
- Lian Li O11D EVO XL case
My main concern is managing temperatures. The Threadripper has a TDP of 350W, and each RTX 5090 draws 575W. I'm debating between a custom loop with dual 480mm radiators or going for an external MORA 420 setup. Has anyone had any experience with similar builds? I'm also a bit worried about fitting everything in the case, even though it's the XL version. Additionally, if the O11D isn't ideal, I'm open to recommendations for other cases. I'm not too restricted on budget as I want to get it right! Thanks for your help!
5 Answers
If space allows, the larger MORA with Noctua 200mm fans is an excellent choice. It's very quiet and efficient, but definitely not the most compact solution. Just keep that in mind!
I've got the O11D case too, and while it's a great case, fitting two 480mm radiators could be a tight squeeze. You might have to use the Lian Li 3 x 120mm fan unit at the bottom to get adequate airflow. Just a heads up, that power supply is excellent for what you're aiming for—seriously top-tier gear!
Have you considered using the RTX Pro 6000 instead of the dual 5090s? It offers more VRAM, which can be beneficial for bigger models and would draw less power overall. Just a thought!
The Pro 6000 is still part of the Lovelace architecture, while the 5090 on Blackwell architecture has better transformer throughput, especially for inference tasks. You might find the 5090 to outperform the Pro 6000 depending on your specific models and setups.
Wow, this setup sounds insane! I can only imagine the performance. Would love to see some pics once you have it all together!
You could check out setups on YouTube! There’s a guy named Optimum Tech who built something similar with a Threadripper and dual 5090s. He provides some solid insights on cooling and layout, particularly about where to place the primary GPU for airflow. If you're not constrained by budget, a custom cooling solution would be your best bet in the long run, even if it requires more maintenance.
Thanks for the tip! I think I’ll pay attention to where the primary GPU is positioned because airflow can make a huge difference. The balance between performance and cooling is crucial for my workloads.

I was looking into the Cooler Master 2000W PSU, but I feel more comfortable with Seasonic's reputation. The reliability data backs them up, and for such an expensive build, I prefer a proven unit.