Which Linux Distro is Best for Digital Artists?

Fedora with the KDE environment is a good call! It's modern and pretty stable. Just be prepared to navigate through the NVIDIA driver setup, but once that's done, it can provide a very satisfying experience similar to what you'd find on the Steam Deck.

Bazzite could be a great choice if you're looking for a SteamOS-like experience, especially if gaming isn't your priority. It offers a Fedora Atomic version that's leaner and doesn’t come packed with gaming tools unless you want them. Just a thought!

For what you're looking for, the choice of distro isn't as crucial as the desktop environment you choose. If you want something that works out of the box with lots of support, I'd suggest Ubuntu, especially the Kubuntu variant. It's got a nice KDE interface that's highly customizable. Fedora is also solid but be ready to tinker a bit with drivers and codecs. For a more fresh experience, consider the latest Kubuntu version over the LTS because this means you won’t have to deal with big upgrades later.

If you want something akin to the Steam Deck, you might want to try something like EndeavourOS with KDE. It's based on Arch Linux, so it’s a bit more challenging, but there's a good community to help you out. For something more user-friendly that still focuses on performance, check out CachyOS, which is optimized for newer hardware like yours.

How about checking out Ubuntu Studio? It comes with the KDE desktop, which has a lot of room for visual tweaks. It also ships with a bunch of creative software that's perfect for artists. Plus, there are guides available online for installing the latest Wacom drivers, should you need them!