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Is It Possible to Use 4x16 GB DDR5 RAM on My PC?

October 26, 2025 5 answers
Asked by TechieGamer42
I've been using a Corsair kit of 2x16 GB DDR5 memory running at 6000 MHz CL36 1.4 V for about a year now. Recently, I started getting low RAM errors in After Effects, so I decided to expand my RAM. I purchased another Corsair 2x16 GB DDR5 kit that runs at the same speed but at 1.35 V. When I try to boot my PC with all four sticks (4x16 GB), it won't start and I see an orange LED on the motherboard. Individually, each kit works fine, but together, they don't. I've tried reducing the frequency to 3600 MHz, adjusting the voltage down to 1.35 V, and testing various slot configurations without success. What else can I attempt before giving up and buying a new 2x32 GB kit?
Corsair RAM DDR5 RAM Hardware memory upgrade motherboard compatibility PC hardware RAM configuration

Answers

MemoryMaster99
Have you considered turning off XMP/EXPO completely? Sometimes that helps resolve compatibility issues.
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PCBuilderGuru
When mixing memory kits, especially with DDR5, you're likely asking for trouble. The differing timings and products can clash in unexpected ways.

CuriousCoder21: I know, right? I consulted an AI about it before checking online, and it suggested I go for it. Major mistake.

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RamWhisperer
Mixing different RAM kits can definitely lead to problems, especially with speeds, timings, and voltages being different. If both kits were a matched 4x16 GB setup, you'd probably have better luck. Generally, 2 sticks tend to work more reliably than 4.
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FirmwareFanatic
Make sure your motherboard's firmware is up to date. Running only 2 DIMMs can be more stable; if you’re still having issues, you might want to consider returning the RAM.

TechieGamer42: I'm actually upgrading the BIOS now.

MemoryMaster99: If you decide to get new RAM, is 5200 MHz fine, or should I stick with 6000 MHz for the best performance?

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CompatibilityChecker
Before purchasing RAM, always check the Qualified Vendor List (QVL) for your motherboard. Generally, a 4 stick setup requires slower memory with looser timings compared to a 2 stick setup, which is usually more stable. Mixing different kits? That’s a big no-no.
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